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Vitreous

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Vitreous

Asteroid bodies

  • Bensons disease
  • 90% unilateral over age 60
  • Calcium soaps attached to fibers

Attachments

  • Posterior lens face
  • Weigers attachment
  • Firm in young people
  • Vitreous base around Ora
  • Very strong attachment
  • Optic nerve
  • Macula
  • Weak oval attachment that weakens more with age

Anterior vitreous detachment

  • Rare due to strong vitreous base attachment
  • Due to trauma
  • Cells in vitreous and visible fibers
  • Probable retinal tear

Posterior vitreous detachment PVD

  • 90% of Aphakes degeneration Follow up in 6 mo.
  • PVD and ring or line floater Follow up in 3 mo.
  • PVD and photopsia Follow up monthly for 3 mo.
  • PVD and pigment in vitreous Follow up weekly for 6 wk’s

Floaters

  • Classic floater shower Vitreous hemorrhage or retinal tear
  • Cobweb shape Vitreous hemorrhage
  • Insect shaped Operculated retinal tear
  • Photopsia in 50% for weeks to years
  • Metamorphopsia from macular edema secondary to tugging at the macula - may lead to a macular hole
  • 10% associated with retinal breaks
  • 50% of retinal detachmentsdo not have history of flashes or floaters
  • 50% of symptomatic retinal breaks progress to retinal detachment
  • 2.5% of symptomatic PVD
  • Acute tears become detached within 6 weeks

Fibrillary degeneration

  • Liquefaction
  • Liquefied vitreous penetrates RPE and pigment is released as “Tobacco dust”
  • Synersis (Shrinking)
  • White without pressure

Genetic disorders

  • Acquired retinoschisis
  • Extends to ora
  • Asymptotic

Amlyoid degeneration of vitreous (Primary heredofamial amyloidosis)

  • Primary
    • Amyloid deposits in heart, thyroid, nerves and muscles
  • Secondary
    • Amyloid deposits in liver, kidneys, adrenals
  • Diplopia
  • Photophobia
  • Vitreous opacities
  • Retinal hemorrhages

Coat's disease (Congenital retinal telangiectasia)

  • Associated with
  • Beading
  • Dilated capillaries
  • Loops
  • Neovascularization
  • Retinal edema
  • Can occur anywhere in the retina
  • Hallmark is localized fusiform dilation of the retinal vessels
  • Effects both arteries and veins
  • Looks like little light bulbs
  • Idiopathic
  • Leaking lipoproteinaceous fluid
  • Yellow-white to green subretinal lipid exudate
  • Lebers miliary aneurysms is a less sever form than Coats
  • May be present at birth, but 1/3 of cases identified are older than 30 when identified
  • Most often male (80%)
  • Treatment is obliterate the telangiectasis and stop the exudation
  • Unilateral
  • Worst case results in:
  • Total exudative retinal detachment
  • Rubeosis irides
  • Glaucoma
  • Phthis bulbi

Coats syndrome (Not congenital or hereditary)

  • Retinal detachment with massive exudation
  • Associated with:
  • Branch retinal vein occlusion
  • Muscular dystrophy
  • Retinitis pigmentosa
  • Retrolental fibroplasia

Congenital hereditary retinoschisis

  • Recessive sex linked primarily males
  • Bilateral splitting of retina in inferior temporal quadrant
  • Normally not out to ora
  • Pigmented demarcation lines
  • Vitreous degeneration
  • Cystic macula changes

Familial exudative vitreoretinopathy

  • Autosomal dominate
  • Bilateral gradual blindness due to neovascularization

Goldmann-Favre’s vitreotapetretinal degeneration

  • Progressive loss of acuity associated with retinoschisis and pigmented chorioretinal degeneration
  • Bilateral autosomal recessive

Wagners hereditary degeneration

  • 100% penetrance
  • Vitreous degeneration at an early age and myopia
  • Gray - white preretinal membranes form and eventual retinal detachment

Paravascular vitreous attachments (Retinal tufts)

  • Strong adhesion between vitreous and equator
  • May lead to retinal detachment

Persistent hyperplastic primary vitreous

  • Anterior
  • Cataracts
  • Glaucoma
  • Microcornea,
  • Failure of regression of primary vitreous
  • Looks like retinopathy of prematurity but in full term no 02 Babies
  • Pale, hypoplastic disc and condensed vitreous
  • Posterior

Snchesis scintillans

  • Bilateral flat cholesterol crystals that sink to bottom
  • Maybe nonexistent condition

Systemic conditions affecting vitreous

Ehlers-Danlos syndrome

  • PVD

Marfans syndrome

  • Vitreous liquefaction
  • PVD

Pseudoxanthoma elasticum

  • Vitreous liquefaction
  • PVD
  • Brown cells in vitreous

Retinitis pigmentosa

  • Vitreous liquefaction
  • PVD
  • Brown cells in vitreous

Vitreous hemorrhage

Retrovitrous

  • Floaters and loss of acuity
  • Bright red blood that moves easily

Intravitrous

  • Blood in vitreous
  • Clots easily
 

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Copyright © 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006 Don Steensma, O.D., F.A.A.O.
Last modified: May 1, 2006