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Accommodation

  • Neural circuit to visual cortex and back

Conjugate gaze

  • Hemisphere damage
  • A hemisphere innervates the ipsilateral MR and the contralateral LR
  • Neither eye can move to contralateral side of damage
  • The patient looks in the direction of the brain damage
  • Medial longitudinal fasiculus damage (Multiple sclerosis most common cause)
  • Decreased ability of both eyes to look medial
  • Convergence remains intact but on versions neither eye will adduct
  • Internuclear ophthalmoplegia

Convergence

  • Mid brain circuit

Dolls head movement

  • Lag of eye position on sudden head movement
  • Brain stem mediated
  • Lack of dolls head would indicate damage to brainstem

Extraocular muscles

  • Controlled by contralateral cortex
  • ER6(SO4)3 enervation
  • Parks 3 step test
  • Hyper: Increase on gaze: Increase on head tilt

Muscle action:

  • IR Depression Adduction Extorsion
  • SR Elevation Adduction Intorsion
  • MR Adduction
  • SO Depression Abduction Intorsion
  • LR Abduction
  • IO Elevation Abduction Extorsion

Muscle fields (Direction of greatest strength)

               SR(3)         IO(3)        SR(3)

                    |                |                |

LR(6) <--| O.D. |--> LR(3) <--| O.S. |--> LR(6)

                   |                 |                |

                IR(3)         SO(4)        IR(3)

  • Rectus muscles act maximally when the eye is deviated temporally
  • Obliques act maximally when nasal
  • Corneal light reflex normally slightly nasal
  • Forced duction test
  • Forced generations test
  • Hirschberg test
  • <K = 0.5 mm nasal
  • 1 mm deviation = 20 prism diopters

Nystagmus

Jerk

  • Unidirectional
  • Paretic muscle increases in direction of muscle direction

Pendular

  • At birth
  • Bilateral
  • Rapid
  • Familial or pathology

Miners

  • After poor illumination for long time

Spasmus Nutans

  • One year old

Seesaw nystagmus

  • MLF syndrome
  • Brainstem lesion

Vestibular nystagmus

  • Constant in all directions of gaze
  • Bi-directional
  • Endpoint
  • Cerebellar lesion

Caloric stimulation

  • Normal
  • Cold water in ear
  • Slow component towards direction of stimulation
  • Fast component away
  • No deviation of eyes

Lethargic

  • Cortex less alert than brain stem so fast component becomes less pronounced and eyes deviate towards damage

Stupor

  • No fast component so eyes deviated to direction of damage

Coma

  • Brain stem also depressed so no deviation or movement

Pupillary reflex's

  • Direct neural circuit from midbrain
  • Fixed and dilated causes
  • Topical meds
  • Jimson weed
  • Scolopamine
  • Intraocular iron foreign body

Vertical gaze

  • Mid brain circuit

Visual field defect

  • Fields in cortex are upside down and backwards to real field
  • Nerve fibers temporal to fovea do not cross. Nasal fibers do cross.
  • Damage to right hemisphere produces loss of left field O.U.
  • Neither eye can see the contralateral side

Pre-chiasmal - Uni-ocular

  • Defect in only one eye
  • Nasal field defect will not go past horizontal

Anterior chiasm

  • Central scotoma and contralateral hemianopsia

Chiasmal - Bitemporal hemianopsia

  • Nasal fibers seeing lateral field decussate
  • Hemispheres receives contralateral field

Post-chaismal - Homonopsia loss of opposite field

  • Anterior cortex lesions may not effect central acuity
  • Posterior cortex lesions reduce acuity
  • Lesion of the lateral geniculate body (LGN)
  • Wedge shaped hemianopsia pointing to fixation
  • Often also have hearing and coordination problems (Proximaty)

Lesion of the temporal lobe

  • Defect densest in superior quadrant ("Pie in the sky")
  • Vertical border always respects midline
  • Often also have speech problems

Lesion of the parietal lobe

  • Defect inferior quadrantopsia ("Pie on the floor")
  • Often also have nystagmus

Lesions of the occipital lobe

  • Most often congruous hemianopsia's
  • Often macular sparing
  • In extreme cases "Cortical Blindness"
  • Blindness denied in Anton's Syndrome

Field Indices

  • False negative indicates inattention
  • False positive indicates anticipation
  • The more sensitive the point the lower the "apostilbs", and the higher the "decibel" (db)
  • Normal "Hill of vision" 29-37 db
  • Drops 3 db for every 10 degrees from fixation
  • Central drops 0.5 db every decade
  • Peripheral drops 0.75-1.00 db every decade

Cranial nerves

CN I Olfactory

  • Closed eyes, nostril occluded, identify smell

CN II Ophthalmic

  • Damage would decrease visual acuity and direct reflex
  • Swinging flashlight test
  • Effected eye shows slight dilation on direct stimulation due to consensual dilation when
  • light is removed from other eye?

CN III Oculomotor nerve

  • Adies pupil (Tonic pupil)
  • Unilateral regular meiosis with slow reflexes and normal mydriatic response
  • Argyle Robertson pupil
  • Indicates Syphilis
  • Bilateral irregular meiosis
  • No direct or consensual reflex with poor mydriatic response

Opthalmoplegia

  • Hypo-exotropia (Can’t look up, down or in)
  • Mydriasis
  • Blur at near
  • Ptosis

Ptosis

  • Lesion of III nerve to levator muscle

  • Lesion of sympathetic pathway of IV nerve

  • Acetylcholine transmission defect (Myasthenia Gravis)

  • Trauma

  • Lid edema

Horners syndrome

  • Miosis
  • Ptosis
  • Anhidrosis due to damage to sympathetic ganglia in neck

CN IV Trochlear nerve

  • Superior oblique muscle (Can’t look down and out)

CN V Trigeminal sensory / motor nerve

  • Distribution on face not back of head
  • Trigeminal neuralgia idiopathic sever pain on one side of face
  • Touch temporal cornea with cotton wisp; Blink?
  • Close eyes and touch each side of face; Same?
  • Clench teeth; Same muscle tone felt on jaw?

CN VI Abducens nerve

  • Lateral recti muscles (Can’t abduct)

CN VII Facial sensory / motor nerve

  • Facial asymmetry
  • Wrinkle brow
  • Close eyes tightly
  • Smile
  • Blow out cheeks
  • Force closed eyes open; Same strength?

CN VIII Auditory nerve

  • Eyes closed and ear covered
  • Rub fingers together and determine how far away heard
  • Weber test
  • 256 HZ/512 HZ tuning fork

CN IX Glossopharyngeal nerve

  • Pronounce vowels
  • Open mouth and inspect for asymmetry See if ulva is pushed to side
  • Touch cotton swab to side of throat and observe gag reflex

CN X Vagus nerve

CN XI Spinal accessory nerve

  • Ask patient to elevate shoulders or turn head each way
  • Compare neck muscle strength

CN XII Hypoglossal nerve

  • Stick out tongue; Is it straight?
  • Repeat tongue twister
  • Push tongue against cheek
  • Cerebral hemisphere damage
  • (Example is if damage to left hemisphere:)
  • Loss of smell left nostril
  • Right homonymous hemianopsia
  • No right conjugate gaze
  • Hemianesthesia of right side of face
  • Only slight chewing defect
  • Lower right facial paralysis

Terminology

Agnosia

  • Not knowing

Apraxia

  • Inability to do a voluntary act

Aphasia

  • Inability to understand or express words

Headache

  • Unilateral more suggestive of mass lesion
  • Throbbing suggests vascular
  • Pulsatile suggests muscle contraction or traction
  • Early AM suggests mass lesion
  • PM suggests muscle contraction (Tension)
  • Stiff neck suggests meningeal irritation

Pain sources

  • Iritis
  • Corneal abrasion
  • Glaucoma
  • Refractive error
  • Muscle imbalance
  • Inflamed or infected sinuses
  • Temporal mandibular joint dysfunction (TMJ)
  • Cervical spine arthritis
  • Neck muscle contraction

Generalized

  • Elevated intra-cranial pressure
  • Hypertension
  • Meningitis
  • Migraine?
  • Psychogenic

Focal

Bilateral

Frontal

  • Frontal sinusitis
  • Maxillary sinusitis
  • Referred

Occipital

  • Cervical lesion
  • Fossa lesion
  • Referred

Midline

  • Sphenoid sinusitis

Unilateral

Shifting (Right, left, right)

  • Migraine

Always same side

  • Arterio-venous malformation
  • Cluster
  • Glaucoma
  • Migraine?
  • Neoplasm
  • Temporal arteritis
  • Trigeminal neuralgia

Cluster headache

  • Type of migrain
  • Men at night

Herpes zoster prodome

  • Periorbital
  • May develop zoster vesicles in 2-5 days

Mass lesion

  • Reproducible in same location
  • Worse in AM - may wake up in night
  • No tumor if central retinal venous pulsation (CRVP)
  • Often memory or personality changes

Migraine headache

  • Due to vasodilation

Classic

  • Aura
  • Headache
  • Vomiting

Common

  • Aura
  • Headache
  • Nausea

Ophthalmic migrain

  • Pain in eye
  • Nausea, vomiting
  • Ophthalmoplegia.
  • Ptosis usually clears in 1 mo.
  • Usually kids

Multiple dystrophy

  • Ptosis
  • Pupil defects

Multiple sclerosis (MS)

  • Ptosis
  • Optic neuritis
  • Uthoff’s sign
  • Decreased acuity in a warm bath

Myasthenia gravis (MG)

  • 20 yr. old 3:1
  • Female
  • Middle age
  • Mainly male
  • 95% have ocular problem
  • Variable muscle weakness

Parkinson's disease

  • Ratcheting movement
  • Shuffling gait
  • Tremor

Temporal arteritis

  • Giant cell arteritis
  • 80% Age 70+
  • Rare in blacks
  • Headache, jaw and scalp pain
  • Stiff neck, shoulders, back, legs
  • loss of visual acuity
  • Throbbing pain at temple
  • Pain on chewing
  • Diagnose by SED rate

Pituitary tumor

  • Superior temporal field defects

Acidophillic

  • Giantism

Basophillic

  • Cushing's syndrome
  • Full face
  • Diabetes
  • Sodium metabolic upset
  • Adiposity

Chromophobe

  • Laurence-Moon-Biedel syndrome
  • Decreased libido
  • Irregular menses
  • Hair and skin changes
  • Adiposity

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Copyright © 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006 Don Steensma, O.D., F.A.A.O.
Last modified: May 1, 2006