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AIDS
- Multitude of signs and symptoms
Acanthosis nigricans
- Benign hyperpigmentations in groin, neck, genitalia
Bechets disease
- Ulceration of genitals, mouth,
- Iritis, scleritis, optic neuritis, vessel sheathing, retinal edema,
glaucoma, cataracts
- More common in Japan
- Treated with steroids
Cicatricial pemphigoid
- Apparent chronic conjunctivitis
- Slowly progressive cicatrization of the conjunctiva and oral mucosa
Dermatomyositis
- Skin rash, proximal muscle weakness, difficult walking, nasal
soundind voice, aspiration, papules on fingers
- Periorbital edema and erythema (Heliotrope)
Erythema multiforme
- Blister formation
- Mild form attacks only hands and feet
- Severe form is Steven-Johnson syndrome
- Young men in spring or fall for 2-3 weeks
- Fever, malaise, headache, urinary infection,
- Bullous red lesion with clear center on extremities and mucous
- Conjunctivitis, sicca, corneal ulcer
- Skin lesions and erosion of mucous membranes
- May be asociated with meds
- Sulfonamides
- Pennisulin
- Aspirin
- Phenylbutazone
- Barbiturates
- Scopolamine
- Sulfonamides
- May follow H. Simplex, measles, vaccination, radiation
Lupus
- Erythematous rash exacerbated by sunlight (Butterfly rash is classic
sign), oral and nasal ulcers
- KCS,SPK,conjunctivitis, episcleritis
- Cotton wool,retinal hemes, retinal occlusion, optic neuropathy,
uveitis
Pemphigus
- Blistering of skin and crusting
- Erosion of eyelid margins and trichiasis
- Conjunctiva slightly injected with slight discharge
Ployartertis nodosa
- Vasculitis of small and medium-size blood vessels
- Skin nodules following the course of superficial arteries
- Retinal vasculitis, CNS changes
Psoriasis
- Red plaques and silvery scales on elbows, knees, ears
- Nail dystrophy
- Conjunctivitis, corneal vascularization and opacities
Reiter's syndrome
- Arthritis, conjunctivitis, urethritis
- Circinate balanitis (Penile vesicles)
- HLA-B27
Relapsing polychondritis
- Auricular chondritis (swelling, erythema, tenderness in the external
ear)
- "Saddle nose"
- KSC, scleritis, corneal infiltrates
Rheumatoid Arthritis
- Rheumatoid nodules, Vasculitis lesions, pyoderma gangrenosum (Necrotic
skin ulcer)
- Sjogren's syndrome, keratitis, scleritis
Sarcoid
- Hilar adenopathy,Erythema nodosum, plaques, nodules, scarring
- Koeppe and Busacca nodules, iritis, venous occlusions
- Granulomas of lid, conjunctiva, lacrimal gland, choroid and optic
nerve
- Retinal periphlebitis with "candle wax" drippings
Scleroderma
- Tight skin,thin pused lips, dull expression
- KCS, cotton wool
Seborrheic blepharitis
- Results in increased meibomian secretions
- Chronic long lasting
- More sever in winter
- Stress and illness exacerbate
- May be auto-immune or may be related to Pityrosporum ovale yeast
- Foamy tears from excess oil
- Greasy scales ("Scurf") that itch surrounded with some
erythema
- Dandruff does not have erythema, only scales
- Most common site is scalp, but also seen on ears, eyebrows and
chest.
- Eczema is a term used in children when the diagnosis is not sure
to be atopic dermatitis or seborrheic dermatitis
Vogt-Koyanagi-Harada
- Alopecia, vitiligo, poliosis
- Uveitis, choroiditis, optic neuritis
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