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490 nm blue light through a 525 nm yellow
- green filter
Phases
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Choroidal flush
- At 10 sec
- Glowing choroid
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Retinal-arterial stage
- At 12 sec
- Central retinal artery
- Retinal-venous stage
- At 13-14 sec
- Laminar flow in veins
- Venous stage
- Exits eye (Returns later more diluted)
- At 20 sec
Prints
- Upper right has name, ect
- #2 & 3 are red-free photos opposite eye
- #4 & 5 are stereo views of involved eye
- #6 with filters in place but before injection
- Next are serial photos taken 2-5 frames/sec
- Final photos are stereo pictures O.U.
Side effects
- 5.4% have side effects
- 2x in males
- Nausea, rash, discolored urine, hives
- Nausea most common side effect
- Starts at 30 sec and lasts 5 min.
- Asthma, syncope, cardiac arrest
Why fluroscein angiography works
- Bruchs membrane permeable
- Choriocapillaris permeable
- RPE impermeable
Hyperfluorescence
- Leakage
- Microaneurysms
- IRMA
- Neovascularization
- Disrupted vessel
Pooling
- Serous detachment of RPE or sensory retina
Staining
- Drusen
- Nerve head
- Occluded vessels
- Vascular inflammation or traction
Transmission defects
Hypoflurescence
- Optical barriers
- RPE hypertrophy
- Hyperplasia
- Pre-retinal or intraretinal bleeding
- Perfusion defects (Occlusion)
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