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Differential

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Aching Eye

  • Acute angle closure glaucoma
  • Para-trigeminal neuralgia
  • Referred headache pain
  • Sinusitis
  • Uveitis
  • Viral myalagia

Allergies

Type I Anaphylactic

  • Mastcells release vasoreactive substance in response to antigen
  • Hayfever

Type II Cytotoxic

  • (Ig)G or (Ig)E antibodies combine with exogenous antigen and attach to cell causing destruction
  • Transplant rejection

Type III Immune complex

  • Antigen-antibody complexes produce inflammatory response
  • Rheumatoid arthritis
  • System lupus erythematosis

Type IV Delayed cell-mediated

  • Antigen-T lymphocyte complex
  • Contact lens solution allergy

Amaurosis

  • Acute angle closure glaucoma
  • Pain
  • Halos
  • Steamy cornea

Papillitis

  • If disc swollen and visual acuity O.K. Papilledema
  • If disc swollen and visual acuity poor Papillitis
  • If disc normal and visual acuity poor Retrobulbar neuritis

Anterior ischemic optic neuropathy (AION )

  • Disk edema
  • Central retinal artery occlusion (CRAO)
  • White retina and "cherry macula"

Cerebral vascular accident (CVA)

  • Involves speech or muscle control

Migraine

  • Scotoma
  • Headache
  • Nausea

Transient ischemic accident (TIA)

  • Confusion
  • Vertigo
  • Blindness for minutes to hours

Ptosis

  • Central
  • Lesion of III nerve to levator muscle
  • Lesion of sympathetic pathway of IV nerve
  • Acetylcholine transmission defect
  • Myasthenia gravis (MG)
  • Lid edema
  • Trauma

New diplopia

  • Diabetes
  • Stroke
  • Trauma
  • Extraocular muscle palsy
  • Facial fracture
  • Orbital emphysema
  • Orbital hemorrhage
  • Orbital herniation

Red Eye

Allergic keratoconjunctivitis

  • Itching
  • Papilla

Bacterial keratoconjunctivitis

  • Discharge

Viral keratoconjunctivitis

  • Infiltrates

  • Follicles

Episcleritis

  • Injection

Glaucoma

  • Edema

Iritis

  • Pain

Trauma

  • History

Sector injection

  • Contact lenses
  • Episcleritis
  • Graves disease
  • Phlyctenular conjunctivitis
  • Ptyrgium
  • Inflamed pinguecula
  • Subconjunctival hemorrhage
  • Sentinel vessel with malignancy

Slowly progressive proptosis

  • Carotid - cavernous fistula

  • Cavernous hemangioma

  • Craniofacial dystosis

  • Orbital pseudotumor

  • Thyroid

  • Tumors

  • Von Ricklinghausens

Sudden onset unilateral pain

  • Abrasion
  • Foreign body
  • Iritis
  • Recurrent corneal erosion (RCE)
  • Retrobulbar neuritis
  • Ulcer or infiltrate

Leukocoria

  • Cataract
  • Coats disease
  • Endophthalmitis
  • Medullated nerve fibers
  • Panophthalmitis
  • Retinoblastoma
  • Toxoplasmosis
  • Tuberculosis

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Copyright © 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006 Don Steensma, O.D., F.A.A.O.
Last modified: May 1, 2006